Working memory, catecholamines and psychosis

Illustrative case

Florence Levy*

*Corresponding author for this work

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Objective: To briefly review the role of catecholamines in prefrontal functions and working memory as illustrated by a case study. Method: The work of Goldman-Rakic and Arnsten on working memory is briefly reviewed. A case study that illustrates catecholamine functions in an autistic disorder child, who suffered a prolonged psychosis, is described. Results: While the role of dopaminergic neurotransmission in working memory has been described, the present case also illustrates a role for a noradrenergic re-uptake inhibitor in treating the post-psychotic distractibility of a severely impaired early adolescent. Conclusion: The role of catecholamine neurotransmitters in the treatment of prefrontal symptoms should be further investigated.

Original languageEnglish
Pages (from-to)74-77
Number of pages4
JournalAustralian and New Zealand Journal of Psychiatry
Volume41
Issue number1
DOIs
Publication statusPublished - Jan 2007
Externally publishedYes

Keywords

  • Dopamine
  • Noradrenaline
  • Prefrontal cortex
  • Psychosis

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