Workshop 1: Understanding non-acute pain in neonates and infants: Where are we at?

K. J. S. Anand, C.-J. van Ganzewinkel, R. R. Pillai Riddell, E. Ilhan

    Research output: Contribution to conferenceAbstract


    Hospitalised neonates and infants are exposed to multiple painful procedures every day. Being non-verbal, this group is particularly vulnerable to ongoing and unrelieved pain. Repetitive exposures to painful, skin- breaking procedures may have short and long–term effects on the developing infant brain and nervous systems. The impact of non-acute pain (e.g. repetitive- episodic, prolonged, persistent, chronic pain) in young infants is largely unknown, and may be at least as significant as its impact on older children and adults. It is believed that these effects include prolonged hospitalisation, impaired growth trajectories, altered pain perception, and impaired neurodevelopment. The lack of a clinically useful framework for non-acute pain in infants and neonates is an obvious barrier to its study. If non-acute pain is not defined, researchers are unable to study its epidemiology, clinical implications, long-term outcomes, or management. More importantly, bedside clinicians are unable to identify when the hospitalised infant transitions from acute painful episodes to sustained non-acute pain states. Previous attempts to define chronic pain in this group were only partially successful; concerted additional efforts are needed to drive progress in this area. Before collecting any data, conceptual frameworks are necessary to frame non-acute pain in infants. The important contributions of parental factors and caregiving practices must be included to understand infants’ behavioural and physiological responses. The role of factors outside the infant’s immediate pain experiences in directing their transition from acute pain to non-acute pain must also be incorporated. This workshop brings together four disciplines to highlight recent efforts and stimulate novel ideas driving research in the area of non-acute pain in neonates and infants. References: 1. van Ganzewinkel, C-J., Anand, K.J.S., Kramer, B.W., & Andriessen, P. (2014). Chronic pain in the newborn: toward a definition. Clinical Journal of Pain, 30, 970 – 977. 2. DiLorenzo, M., Pillai Riddell, R., Holstii, L. (2016). Beyond acute pain: understanding pain that persists in infancy. Children, 3, 26. doi:10.3390/children3040026. 3. Anand, K.J.S. (2017). Defining pain in newborns: need for a uniform taxonomy? Acta Paediatrica, 106, 1438-44.
    Original languageEnglish
    Publication statusPublished - 16 Jun 2019
    EventInternational Symposium on Pediatric Pain - Basel, Switzerland, Basel, Switzerland
    Duration: 16 Jun 201920 Jun 2019


    ConferenceInternational Symposium on Pediatric Pain


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