Yeast systems biology: modelling the winemaker's art

Anthony R. Borneman*, Paul J. Chambers, Isak S. Pretorius

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

25 Citations (Scopus)

Abstract

Yeast research represents an important nexus between fundamental and applied research. Just as fundamental yeast research transitioned from classical, reductionist strategies to whole-genome techniques, whole-genome studies are advancing to the next level of biological research, referred to as systems biology. Industries that rely on high-performing yeast, such as the wine industry, are therefore poised to reap the many benefits that systems biology can provide. This includes the promise of strain development at speeds and costs which are unobtainable using current techniques. This article reviews the current state of whole-genome techniques available to yeast researchers and outlines how these processes can be used to obtain 'systems-level' information to provide insights into winemaking.

Original languageEnglish
Pages (from-to)349-355
Number of pages7
JournalTrends in Biotechnology
Volume25
Issue number8
DOIs
Publication statusPublished - Aug 2007
Externally publishedYes

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